Heat Vision and Jack was created as a 1999 pilot for Fox. Written by Dan Harmon and Rob Schrab, directed by Ben Stiller, this series was passed over by Fox despite critical acclaim from those who've been lucky enough to see it.
The pilot was never aired on television, but has recently been screened at several film festivals and was very well received by crowds. HV&J recently won the Silver Spire award at the San Francisco International Film Festival.
The 30 minute pilot is about an astronaut (played by Jack Black) with a medical secret is on the run from his evil employers with the help of a talking motorcycle called Heat Vision (voiced by Owen Wilson).
(From the unofficial Heat Vision and Jack website)